Proprietary Work

Global Value Dossiers

Global dossiers to support the market access function, these synthesize relevant clinical and economic research, publicly accessible literature and market strategy and present an evidence-based value rationale. We have developed these for pipeline or approved products in a variety of therapeutic areas… cardiology, gastroenterology, infectious disease, neurology, oncology, psychiatry, rheumatology, …

Formulary submission packages

Over 200 submissions to Canadian and US formulary decisionmakers prepared to date, including clinical and economic background and rationale, budget impact models and reports, product-specific and audience-specific forms and reports

Presentation materials

Posters, slides, handouts, and other presentation materials for in-house or external dissemination of health outcomes information, research and strategy (Posters, Podiums and Keynote presentations, classroom or conference room materials)

Backgrounders, Briefing Documents & Reports (for example…)

  • Economic evaluation of vancomycin and fidaxomicin for the treatment of clostridium difficile infection in Canada
  • Literature review and critical analysis of the burden of Varicella infection
  • Literature review and gap analysis of depot antipsychotic medications for schizophrenia and their effect on compliance and outcomes
  • Systematic review of the natural history of HPV infection and associated diseases in females 9-26
  • Systematic literature review on the clinical and economic burden and treatment of heart failure in Canada
  • Gap analysis for diagnostic medical device used for the detection of H. pylori. in Ontario
  • Human Papilloma virus (HPV): homosexual transmission and burden of disease
  • Human Papilloma virus (HPV): heterosexual transmission and burden of disease
  • A common road map for data synthesis, clinical practice guidelines and policymaking—applications of the EVIDEM framework
  • Antithrombotic therapy for prevention of stroke in atrial fibrillation: disease burden and unmet needs
  • Étude de la faisabilité de la mise en place d'une banque de lait maternel chez Héma-Québec
  • Canadian Workplace Health Promotion programs; health and economic outcomes
  • Aspects of workplace disease management and employee health in Canada
  • Global clinical and economic burden of nosocomial infections - with a focus on S aureus and post-surgical infection
  • Health policy study examining the cost of oncology medicines in Canada
  • Literature review on the natural history of human papillomavirus (HPV) infection and associated diseases in men
  • The value of pharmaceutical innovation in Canada
  • The natural history of human papillomavirus (HPV) infection in adult women
  • Epidemiological and etiological aspects of CABP and cSSSi
  • Clinical, pharmacoeconomic and quality of life evidence for direct renin inhibitors, angiotensin II receptor blockers and angiotensin-converting enzyme inhibitors for all indications
  • Systematic review of the biomedical literature on the topic of stable angina, its epidemiology, treatment and burden
  • Comprehensive review of the biomedical literature on the topic of risk of metabolic syndrome in patients treated with the atypical antipsychotics
  • Systematic review of biomedical literature: rotavirus epidemiology and burden of illness in the middle east and Europe
  • Systematic literature review and gap analysis: negative pressure wound healing
  • Comprehensive literature review of opioid-induced constipation: epidemiology, health care utilization, quality of life and clinical
  • Antithrombotic therapy for prevention of stroke in atrial fibrillation: evidence on disease burden and unmet need
  • An analysis of sub-optimal coagulation treatment for atrial fibrillation
  • A comprehensive review of the burden of disease and unmet needs for prevention and treatment of venous thromboembolism (VTE) in the medically ill
  • The association between anal intraepithelial neoplasia (AIN) and anal cancer
  • Atrial fibrillation patient subgroup analysis
  • Costs of urinary tract infections in Germany, the UK and USA
  • The role of HTA in healthcare decisionmaking: a report on selected drug policy issues in Canada
  • Aspects of the natural history of human papillomavirus (HPV) infection and associated diseases
  • A systematic review of health related quality of life and ostomy treatment
  • Assessing the future of 'authorized generics' in a number of  market segments - US, UK, France & Japan
  • Renal anemia and EPO: the pre-dialysis renal anemia market
  • Venous leg ulcers: patient compliance and impact on clinical and economic outcomes
  • Canadianizing an economic model comparing intensive atorvastatin treatment with standard simvastatin treatment based on data from the CARDS trial
  • Cytomegalovirus (CMV): Biomarkers of congenital infection & disease and relationships
  • Vaccination programs for pneumococcal disease in adults (≥50 years): Evidence for disease burden and unmet needs
  • Vaccination programs for pneumococcal disease in the pediatric population: Evidence on disease burden and unmet needs
  • Pneumococcal vaccine development in the post-Prevnar era: key issues in epidemiology and economic modeling
  • Glaucoma (IOP) treatment in Canada
  • Overview of HPV Vaccination
  • Overview of hip fracture
  • Reimbursement and J-Code incentives for pharmacological stress test drugs (adenosine, dipyridamole, dobutamine) in the US
  • Overview of DPP-4 inhibitors for diabetes
  • Costs of short and long term disability in Type II diabetes relating to poor glycemic control from the perspective of 3rd party payers
  • The burden of major depressive disorder (MDD)
  • Tabulation of health and economic outcome measures (number needed-to-treat and cost per quality adjusted life year) used for medical interventions in Canada and the US
  • Osteoarthritis and rheumatoid arthritis in Canada
  • Pharmacoeconomic assessment of medication for treatment of ulcers and gastroesophageal reflux disease (GERD)
  • Comparison of NSAID + PPI treatment versus COX-2 selective inhibitors on NSAID-related gastrointestinal events
  • Status of Paget's Disease:  treatment and current practice in Canada
  • Vitamin D and osteoporosis
  • Marketing of pharmaceutical products in the 1980s and 1990s
  • Sarcopenia and cachexia: burden of illness and management patterns
  • Congestive heart failure (CHF) in Ontario and Quebec
  • Rates of nausea & vomiting and sexual dysfunction with SSRI & SNRI antidepressant use, impact on compliance, and effect of compliance on depression outcomes
  • Cost-of-illness of acromegaly and associated co-morbidities
  • Acromegaly and associated comorbidities
  • Haloperidol treatment for schizophrenia
  • Use of biologics in Canada
  • Risperidone treatment for schizophrenia
  • Oral inflammation and human systemic disease [Full Text available]
  • Drivers of healthcare cost growth in the US
  • Treatment of dyslipidemia
  • The limitations of statin therapy in the treatment of hypercholesterolemia
  • Prostate cancer treatment in Canada: current status and research investment
  • Salmon calcitonin nasal spray (Miacalcin) for osteoporosis treatment
  • Economic and quality of life outcomes in renal and oncology-related anemia
  • The science behind Colgate Total
  • The market for non-pharmacological approaches to deep vein thrombosis (DVT) treatment
  • Managing escalating pharmaceutical costs: challenges facing pharmacy services
  • Economic evaluation and quality of life in solid organ transplantation
  • New approaches to therapeutic intervention in cardiac hypertrophy
  • Forces influencing inpatient hospital costs in the United States
  • The role of Triclosan/Copolymer dentifrice in the prevention and control of periodontal disease

Patient Information & Educational Materials …)

= Full text available
  • Harvard Continuing Medical Education for Dental Health Professionals
    Quarterly continuing education test material based on oral health research, 1996 to present
  • Manuel de transplantation pulmonaire/Lung transplantation manual
    Multidisciplinary bilingual informational package for patients undergoing lung transplantation
  • Major published clinical trials in the treatment of rheumatoid arthritis and osteoarthritis
    Structured multimedia summaries of pivotal studies in rheumatology for CME
  • Accreditation course modules
    Review, evaluation of and report on 13 modules used for basic biomedical and pharmacology training of pharmaceutical sales and marketing personnel
  • Biomedical course modules
    A series of multimedia materials prepared for basic biomedical training of pharmaceutical personnel